"The great gun guru Jeff Cooper, who considered the 9mm impotent, once said that no gun fit his hand better than the High Power, and it was a shame it was not chambered for a caliber of consequence."
As a matter of fact, BHP's were manufactured for a couple of decades in .40 S&W. Apparently someone listened.
FN/Browning had to design the Mk. III BHP in order "barely" handle the ,40 S&W. And still that variant was not a commercial success because the .40 S&W was hard on it. But, the Mk. III did result in the strongest 9mm of the entire BHP series.
Because of it's design and idiosyncracies the only "caliber of consequence" the BHP could be successful with is the 9mm Luger.