It really is a good question, for me I'm not sure I can prepare for doomsday/armageddon, I mean if it actually gets that far, I don't imagine there will me much left anyway....
Now for anything not nuclear/asteroid related I'm in a bit of a pickle...I live in an apartment building, and strategically I'm in a good position, I only have one side of my unit facing outside, everything else is internal shared walls, I have a ground floor entrance, but 90% of my home is 2nd & 3rd floors, so I have 1 main door, one garage door, one balcony door and two windows that could be points of entry...so barricades on the doors and people in both windows covers me "fairly" well...unless "they" burn the damn building down.
So, unless I have to bug out (which we have a plan for), I intend to hunker down with my stuff, we're relatively well armed, and have stockpiles of food/water/ammo for a period of time, and we have two Bluetti battery banks with solar panels for the balcony to keep our basics running if the power actually cuts. We also have a Ring security system with six cameras in all the appropriate spots, so as long as I have power, I can see what's going on outside without putting my head (target) in the window.
My wife thinks I'm a little nuts, but this stuff actually keeps me awake sometimes...it didn't use to, but in today's climate, it certainly does.