Unless the ammo states "short barrel" you should be gtg. +p is the way to go as long as it's safe in that firearm. I've run wwb ammo in the vector w/o issues. Defense ammo might not be a good choice. Pressure isn't the issue on longer barrels, it's gas volume. I can only test commercial powders as factory powders are different in most cases. Actually the bullets don't slow down, the don't maintain the save added fps per inch (25fps being average, but more like 10fps after 10"). I haven't confirmed yet as I haven't chronographed any.