What vitals? A side shot into the heart/lung area, or directly into the brain thru the skull in a frontal shot?
I see no language in his (the featured) article about the 10mm, nor the 45+P penetrating deep enough.
Keep in mind a fatally wounded griz/brown bear will still kill someone if you don't shut down the CPU.
In his OP article it's the author's opinion is a standard velocity .45 FMJ is adequate for deep penetration. But in the "linked-to" Buffalo Bore states a couple of their loads are designed for deeper penetration, and there's nothing in the Buffalo Bore linked to page about the .45+p being better..
Since the author lives in Texas where there are no Griz, his opinion is pretty weak outside of the conditions that he's used to encounter in TX.